2. Gene
  3. Gjb4 - gap junction protein, beta 4 Gene

Gjb4 - gap junction protein, beta 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cxnb; Gjb-4; Cx30.3; Cnx30.3

Gene ID: 14621 | Gene type: protein coding

About Gjb4

Summary

Enables gap junction channel activity. Involved in cell-cell signaling and gap junction-mediated intercellular transport. Acts upstream of or within olfactory behavior and sensory perception of smell. Is integral component of plasma membrane. Part of connexin complex. Is expressed in early conceptus; gut; male reproductive gland or organ; metanephros; and skin. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and erythrokeratodermia variabilis et progressiva 2. Orthologous to human GJB4 (Gap Junction Protein beta 4). [provided by Alliance of Genome Resources, Apr 2022]

Gjb4 Products(1)

mRNA Protein Name
NM_008127.4 NP_032153.1 gap junction beta-4 protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables gap junction channel activity IDA
IDA: Inferred from direct assay
15692151 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15692151 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cell-cell signaling IDA
IDA: Inferred from direct assay
15692151 MGI
involved in gap junction-mediated intercellular transport IDA
IDA: Inferred from direct assay
15692151 MGI
acts upstream of or within olfactory behavior IMP
IMP: Inferred from mutant phenotype
17728008 MGI
acts upstream of or within sensory perception of smell IMP
IMP: Inferred from mutant phenotype
17728008 MGI
Cellular Component GO Annotation Evidence Reference Source
part of connexin complex IDA
IDA: Inferred from direct assay
15692151 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15692151 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction beta-4 protein

connexin b

connexin-30.3

gap junction membrane channel protein beta 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05449 GJB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjb4 NCBI NCBI:127534