Gjb4 - gap junction protein, beta 4 Gene

Also Known as Cxnb; Gjb-4; Cx30.3; Cnx30.3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14621

Summary

Enables gap junction channel activity. Involved in cell-cell signaling and gap junction-mediated intercellular transport. Acts upstream of or within olfactory behavior and sensory perception of smell. Is integral component of plasma membrane. Part of connexin complex. Is expressed in early conceptus; gut; male reproductive gland or organ; metanephros; and skin. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and erythrokeratodermia variabilis et progressiva 2. Orthologous to human GJB4 (Gap Junction Protein beta 4). [provided by Alliance of Genome Resources, Apr 2022]

Gjb4 Products (1)

mRNA Protein Name
NM_008127.4 NP_032153.1 gap junction beta-4 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables gap junction channel activity IDA
IDA: Inferred from direct assay
15692151 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15692151 MGI
Biological Process GO Annotation Evidence References Source
involved in cell-cell signaling IDA
IDA: Inferred from direct assay
15692151 MGI
involved in gap junction-mediated intercellular transport IDA
IDA: Inferred from direct assay
15692151 MGI
acts upstream of or within olfactory behavior IMP
IMP: Inferred from mutant phenotype
17728008 MGI
acts upstream of or within sensory perception of smell IMP
IMP: Inferred from mutant phenotype
17728008 MGI
Cellular Component GO Annotation Evidence References Source
part of connexin complex IDA
IDA: Inferred from direct assay
15692151 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15692151 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction beta-4 protein

  • connexin b

  • connexin-30.3

  • gap junction membrane channel protein beta 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05449 GJB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjb4 NCBI NCBI:127534