2. Gene
  3. Gnat2 - G protein subunit alpha transducin 2 Gene

Gnat2 - G protein subunit alpha transducin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gt-2; Hg1d; Gnat-2; Tcalpha

Gene ID: 14686 | Gene type: protein coding

About Gnat2

Summary

Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Acts upstream of or within detection of light stimulus involved in visual perception; phototransduction; and retinal cone cell development. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in photoreceptor inner segment and photoreceptor outer segment. Is expressed in early conceptus; primary oocyte; retina; retina outer nuclear layer; and secondary oocyte. Used to study achromatopsia 4. Human ortholog(s) of this gene implicated in achromatopsia 4 and color blindness. Orthologous to human GNAT2 (G protein subunit alpha transducin 2). [provided by Alliance of Genome Resources, Apr 2022]

Gnat2 Products(1)

mRNA Protein Name
NM_008141.3 NP_032167.1 guanine nucleotide-binding protein G(t) subunit alpha-2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within L-glutamate import IMP
IMP: Inferred from mutant phenotype
24403163 MGI
acts upstream of or within background adaptation IMP
IMP: Inferred from mutant phenotype
24373883 MGI
acts upstream of or within camera-type eye development IMP
IMP: Inferred from mutant phenotype
32049342 MGI
acts upstream of or within cell morphogenesis IMP
IMP: Inferred from mutant phenotype
23580486 MGI
acts upstream of or within cone retinal bipolar cell differentiation IMP
IMP: Inferred from mutant phenotype
23580486 MGI
acts upstream of or within detection of light stimulus IDA
IDA: Inferred from direct assay
19815523 MGI
acts upstream of or within detection of light stimulus IGI
IGI: Inferred from genetic interaction
19815523 MGI
acts upstream of or within detection of light stimulus IMP
IMP: Inferred from mutant phenotype
19815523 MGI
acts upstream of or within detection of light stimulus involved in visual perception IMP
IMP: Inferred from mutant phenotype
17065522 MGI
acts upstream of or within dopamine metabolic process IMP
IMP: Inferred from mutant phenotype
32049342 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
23580486 MGI
acts upstream of or within homeostasis of number of retina cells IMP
IMP: Inferred from mutant phenotype
23580486 MGI
acts upstream of or within neural tissue regeneration IGI
IGI: Inferred from genetic interaction
30111842 MGI
acts upstream of or within phototransduction IMP
IMP: Inferred from mutant phenotype
17408617 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
23580486 MGI
acts upstream of or within reactive gliosis IMP
IMP: Inferred from mutant phenotype
23580486 MGI
acts upstream of or within response to UV IMP
IMP: Inferred from mutant phenotype
32049342 MGI
acts upstream of or within response to light intensity IMP
IMP: Inferred from mutant phenotype
20844144 MGI
acts upstream of or within response to light stimulus IDA
IDA: Inferred from direct assay
19815523 MGI
acts upstream of or within response to light stimulus IGI
IGI: Inferred from genetic interaction
19815523 MGI
acts upstream of or within response to light stimulus IMP
IMP: Inferred from mutant phenotype
19815523 MGI
acts upstream of or within response to organic cyclic compound IMP
IMP: Inferred from mutant phenotype
31537864 MGI
acts upstream of or within retinal cone cell development IMP
IMP: Inferred from mutant phenotype
17065522 MGI
acts upstream of or within retinal cone cell differentiation IDA
IDA: Inferred from direct assay
19815523 MGI
acts upstream of or within retinal cone cell differentiation IGI
IGI: Inferred from genetic interaction
19815523 MGI
acts upstream of or within retinal cone cell differentiation IMP
IMP: Inferred from mutant phenotype
19815523 MGI
acts upstream of or within retinal rod cell differentiation IDA
IDA: Inferred from direct assay
19815523 MGI
acts upstream of or within retinal rod cell differentiation IGI
IGI: Inferred from genetic interaction
19815523 MGI
acts upstream of or within retinal rod cell differentiation IMP
IMP: Inferred from mutant phenotype
19815523 MGI
acts upstream of or within tissue remodeling IMP
IMP: Inferred from mutant phenotype
23580486 MGI
acts upstream of or within visual behavior IMP
IMP: Inferred from mutant phenotype
20844144 MGI
acts upstream of or within visual perception IGI
IGI: Inferred from genetic interaction
30111842 MGI
acts upstream of or within visual perception IMP
IMP: Inferred from mutant phenotype
17515894 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in synapse IMP
IMP: Inferred from mutant phenotype
24403163 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(t) subunit alpha-2

guanine nucleotide binding protein, alpha transducing 2

heterotrimeric guanine nucleotide-binding protein 1d

transducin alpha-2 chain

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05542 GNAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnat2 NCBI NCBI:2780