Gnpat - glyceronephosphate O-acyltransferase Gene

Also Known as DHAPAT; D1Ertd819e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14712

Summary

Enables glycerone-phosphate O-acyltransferase activity. Acts upstream of or within several processes, including cell junction assembly; cerebellum morphogenesis; and ether lipid biosynthetic process. Predicted to be located in mitochondrion and peroxisome. Predicted to be active in mitochondrial membrane and peroxisomal membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study disease of mental health and rhizomelic chondrodysplasia punctata type 2. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata type 2. Orthologous to human GNPAT (glyceronephosphate O-acyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Gnpat Products (1)

mRNA Protein Name
NM_010322.3 NP_034452.3 dihydroxyacetone phosphate acyltransferase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables catalytic activity IDA
IDA: Inferred from direct assay
10456321 MGI
enables glycerone-phosphate O-acyltransferase activity IDA
IDA: Inferred from direct assay
10395968 MGI
enables glycerone-phosphate O-acyltransferase activity IMP
IMP: Inferred from mutant phenotype
12874108 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cerebellum morphogenesis IMP
IMP: Inferred from mutant phenotype
19270340 MGI
acts upstream of or within ether lipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
12874108 MGI
acts upstream of or within membrane organization IMP
IMP: Inferred from mutant phenotype
12874108 MGI
acts upstream of or within myelination IMP
IMP: Inferred from mutant phenotype
19270340 MGI
acts upstream of or within paranodal junction assembly IMP
IMP: Inferred from mutant phenotype
19270340 MGI
acts upstream of or within synapse assembly IMP
IMP: Inferred from mutant phenotype
19270340 MGI
Cellular Component GO Annotation Evidence References Source
located in peroxisome IDA
IDA: Inferred from direct assay
10456321 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dihydroxyacetone phosphate acyltransferase

  • DAP-AT

  • DHAP-AT

  • acyl-CoA:dihydroxyacetonephosphateacyltransferase

  • glycerone-phosphate O-acyltransferase

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1465 1-Hexadecanol 99.76% Unkown

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05570 GNPAT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnpat NCBI NCBI:8443