Gpam - glycerol-3-phosphate acyltransferase, mitochondrial Gene

Also Known as P90; GPAT; GPAT1; GPAT-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14732

Summary

Enables glycerol-3-phosphate O-acyltransferase activity. Acts upstream of or within several processes, including glycerolipid metabolic process; lipid homeostasis; and negative regulation of activation-induced cell death of T cells. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human GPAM (glycerol-3-phosphate Acyltransferase, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Gpam Products (3)

mRNA Protein Name
NM_001356285.2 NP_001343214.1 glycerol-3-phosphate acyltransferase 1, mitochondrial
NM_001410454.1 NP_001397383.1 glycerol-3-phosphate acyltransferase 1, mitochondrial
NM_008149.4 NP_032175.2 glycerol-3-phosphate acyltransferase 1, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glycerol-3-phosphate O-acyltransferase activity IDA
IDA: Inferred from direct assay
12417724 MGI
enables glycerol-3-phosphate O-acyltransferase activity IMP
IMP: Inferred from mutant phenotype
12417724 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of activated T cell proliferation IMP
IMP: Inferred from mutant phenotype
18971390 MGI
acts upstream of activation-induced cell death of T cells IMP
IMP: Inferred from mutant phenotype
18971390 MGI
acts upstream of or within acyl-CoA metabolic process IMP
IMP: Inferred from mutant phenotype
15878874 MGI
acts upstream of or within defense response to virus IMP
IMP: Inferred from mutant phenotype
19193813 MGI
acts upstream of or within fatty acid homeostasis IMP
IMP: Inferred from mutant phenotype
18522808 MGI
acts upstream of or within fatty acid metabolic process IMP
IMP: Inferred from mutant phenotype
12417724 MGI
acts upstream of or within glycerophospholipid metabolic process IMP
IMP: Inferred from mutant phenotype
18971390 MGI
acts upstream of or within interleukin-2 production IMP
IMP: Inferred from mutant phenotype
18971390 MGI
acts upstream of or within negative regulation of activation-induced cell death of T cells IMP
IMP: Inferred from mutant phenotype
18971390 MGI
acts upstream of or within phospholipid homeostasis IMP
IMP: Inferred from mutant phenotype
18522808 MGI
acts upstream of or within positive regulation of activated T cell proliferation IMP
IMP: Inferred from mutant phenotype
18971390 MGI
acts upstream of or within positive regulation of multicellular organism growth IMP
IMP: Inferred from mutant phenotype
12417724 MGI
acts upstream of or within regulation of cytokine production IMP
IMP: Inferred from mutant phenotype
18971390 MGI
acts upstream of or within response to glucose IMP
IMP: Inferred from mutant phenotype
15878874 MGI
involved in triglyceride biosynthetic process IMP
IMP: Inferred from mutant phenotype
12417724 MGI
acts upstream of or within triglyceride metabolic process IMP
IMP: Inferred from mutant phenotype
15878874 MGI
Cellular Component GO Annotation Evidence References Source
is active in mitochondrial outer membrane IMP
IMP: Inferred from mutant phenotype
18339309 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
12417724 MGI
located in mitochondrion IMP
IMP: Inferred from mutant phenotype
18339309 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerol-3-phosphate acyltransferase 1, mitochondrial

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05615 GPAM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20747 Gpam Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27259 Gpam Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpam NCBI NCBI:57678