Gpm6b - glycoprotein m6b Gene
Also Known as M6B; Gpm6
Species: Mus musculus
Gene Type: protein coding
Gene ID: 14758
Summary
Involved in negative regulation of protein localization to cell surface and negative regulation of serotonin uptake. Located in membrane raft and plasma membrane. Is expressed in central nervous system; early nephron; gonad; and retina. Orthologous to human GPM6B (glycoprotein M6B). [provided by Alliance of Genome Resources, Apr 2022]
Gpm6b Products (9)
| mRNA | Protein | Name |
|---|---|---|
| NM_001177955.1 | NP_001171426.1 | neuronal membrane glycoprotein M6-b isoform 1 |
| NM_001177956.1 | NP_001171427.1 | neuronal membrane glycoprotein M6-b isoform 2 |
| NM_001177957.1 | NP_001171428.1 | neuronal membrane glycoprotein M6-b isoform 2 |
| NM_001177958.1 | NP_001171429.1 | neuronal membrane glycoprotein M6-b isoform 3 |
| NM_001177959.1 | NP_001171430.1 | neuronal membrane glycoprotein M6-b isoform 5 |
| NM_001177960.1 | NP_001171431.1 | neuronal membrane glycoprotein M6-b isoform 5 |
| NM_001177961.1 | NP_001171432.1 | neuronal membrane glycoprotein M6-b isoform 6 |
| NM_001177962.1 | NP_001171433.1 | neuronal membrane glycoprotein M6-b isoform 6 |
| NM_023122.3 | NP_075611.1 | neuronal membrane glycoprotein M6-b isoform 4 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in negative regulation of protein localization to cell surface |
IDA
IDA: Inferred from direct assay
|
18581270 | MGI |
| involved in negative regulation of serotonin uptake |
IDA
IDA: Inferred from direct assay
|
18581270 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in membrane raft |
IDA
IDA: Inferred from direct assay
|
18581270 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
18581270 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
neuronal membrane glycoprotein M6-b |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS05644 | GPM6B Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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