Grid1 - glutamate receptor, ionotropic, delta 1 Gene

Mus musculus

Also known as GluD1; GluRdelta1

Gene ID: 14803 | Gene type: protein coding

About Grid1

Summary

Predicted to enable glutamate receptor activity; identical protein binding activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in social behavior. Located in glutamatergic synapse. Is integral component of postsynaptic density membrane. Is expressed in several structures, including alimentary system; brain; liver and biliary system; reproductive system; and spinal cord. Orthologous to human GRID1 (glutamate ionotropic receptor delta type subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Grid1 Products(1)

mRNA	Protein	Name
NM_008166.2	NP_032192.2	glutamate receptor ionotropic, delta-1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12372286	MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA IDA: Inferred from direct assay	28696429	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of postsynapse organization	EXP EXP: Inferred from Experiment	25721396	MGI
involved in regulation of postsynapse organization	IDA IDA: Inferred from direct assay	25721396	MGI
involved in regulation of postsynapse organization	IEP IEP: Inferred from expression pattern	25721396	MGI
involved in regulation of postsynapse organization	IMP IMP: Inferred from mutant phenotype	25721396	MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels	IDA IDA: Inferred from direct assay	34135511	MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels	IMP IMP: Inferred from mutant phenotype	34135511	MGI
involved in social behavior	IMP IMP: Inferred from mutant phenotype	22412961	MGI
involved in synaptic signaling via neuropeptide	IDA IDA: Inferred from direct assay	28696429	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in GABA-ergic synapse	IDA IDA: Inferred from direct assay	31704028	MGI
is active in glutamatergic synapse	EXP EXP: Inferred from Experiment	25721396	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	25001082	MGI
is active in glutamatergic synapse	IEP IEP: Inferred from expression pattern	25721396	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	25721396	MGI
is active in postsynaptic density membrane	IDA IDA: Inferred from direct assay	25001082	MGI
is active in postsynaptic membrane	IDA IDA: Inferred from direct assay	31704028	MGI
located in postsynaptic membrane	IDA IDA: Inferred from direct assay	34135511	MGI
part of trans-synaptic protein complex	IDA IDA: Inferred from direct assay	34135511	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

glutamate receptor ionotropic, delta-1

gluR delta-1 subunit

glutamate receptor delta-1 subunit

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05795	GRID1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Grid1	NCBI	NCBI:2894

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