Grin2d - glutamate receptor, ionotropic, NMDA2D (epsilon 4) Gene

Also Known as NR2D; GluN2D; NMDAR2D

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14814

Summary

Enables NMDA glutamate receptor activity. Acts upstream of or within adult locomotory behavior; regulation of sensory perception of pain; and startle response. Located in synapse. Is expressed in brain. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 46. Orthologous to human GRIN2D (glutamate ionotropic receptor NMDA type subunit 2D). [provided by Alliance of Genome Resources, Apr 2022]

Grin2d Products (1)

mRNA Protein Name
NM_008172.3 NP_032198.2 glutamate receptor ionotropic, NMDA 2D precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables NMDA glutamate receptor activity IDA
IDA: Inferred from direct assay
1385220 MGI
enables NMDA glutamate receptor activity IMP
IMP: Inferred from mutant phenotype
12832518 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adult locomotory behavior IMP
IMP: Inferred from mutant phenotype
8774946 MGI
NOT acts upstream of or within detection of mechanical stimulus involved in sensory perception of pain IMP
IMP: Inferred from mutant phenotype
16190898 MGI
NOT acts upstream of or within excitatory postsynaptic potential IMP
IMP: Inferred from mutant phenotype
12832518 MGI
acts upstream of or within regulation of sensory perception of pain IMP
IMP: Inferred from mutant phenotype
10771345 MGI
acts upstream of or within startle response IMP
IMP: Inferred from mutant phenotype
9718984 MGI
Cellular Component GO Annotation Evidence References Source
located in synapse IDA
IDA: Inferred from direct assay
8774946 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutamate receptor ionotropic, NMDA 2D

  • GluRepsilon4

  • N-methyl D-aspartate receptor subtype 2D

  • glur epsilon 4

  • glutamate [NMDA] receptor subunit epsilon-4

  • ionotropic NMDA glutamate receptor epsilon 4 subunit type 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05805 GRIN2D Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grin2d NCBI NCBI:2906