Gsx1 - GS homeobox 1 Gene

Also Known as Gsh1; Gsh-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14842

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within nervous system development. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human GSX1 (GS homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Gsx1 Products (1)

mRNA Protein Name
NM_008178.3 NP_032204.1 GS homeobox 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
11731616 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
11731616 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11731616 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8589431 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adenohypophysis development IMP
IMP: Inferred from mutant phenotype
8631293 MGI
acts upstream of or within hypothalamus development IMP
IMP: Inferred from mutant phenotype
8631293 MGI
acts upstream of or within neuron fate commitment IGI
IGI: Inferred from genetic interaction
16715081 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11731616 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
8631293 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
11731616 MGI
acts upstream of or within spinal cord association neuron differentiation IGI
IGI: Inferred from genetic interaction
16715081 MGI
acts upstream of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
8631293 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GS homeobox 1

  • genomic screened homeo box 1

  • homeobox protein GSH-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05890 GSX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gsx1 NCBI NCBI:219409