PHF13 - PHD finger protein 13 Gene

Also Known as PHF5; SPOC1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 148479

About PHF13

Cytogenetic location: 1p36.31 Genomic coordinates (GRCh38): 1:6,613,731-6,624,030 (from NCBI)

This gene has 2 transcripts (splice variants), 191 orthologues and 1 paralogue. Broad expression in testis (RPKM 26.3), endometrium (RPKM 8.4) and 25 other tissues.

Summary

Enables chromatin binding activity. Involved in mitotic chromosome condensation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PHF13 Products (1)

mRNA Protein Name
NM_153812.3 NP_722519.2 PHD finger protein 13

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables chromatin binding IDA
IDA: Inferred from direct assay
19638409 GOA
enables chromatin-protein adaptor activity IDA
IDA: Inferred from direct assay
23034801 GOA
enables methylated histone binding IDA
IDA: Inferred from direct assay
23034801 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
23034801 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in chromosome segregation IMP
IMP: Inferred from mutant phenotype
19638409 GOA
involved in mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
19638409 GOA
involved in mitotic chromosome condensation IMP
IMP: Inferred from mutant phenotype
19638409 GOA
involved in regulation of DNA repair IDA
IDA: Inferred from direct assay
23034801 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in nucleus IDA
IDA: Inferred from direct assay
19638409 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PHF13 Protein Structure

PHD

PHD: PHD-finger (235 - 279)

  • 0
  • 100
  • 200
  • 300 a.a.
Protein Preferred Names Protein Names

PHD finger protein 13

  • PHD zinc finger protein PHF5

Related Diseases

Diseases Alias
Ovarian Cancer 1

  • Ovarian Cancer, Susceptibility To

  • Ovarian Cancer, Susceptibility To, 1

  • OVCAS1

  • Ovarian Cancer

  • Ovarian Carcinoma

  • Malignant Neoplasm Of Ovary

  • Epithelial Ovarian Cancer
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Pick Disease Of Brain

  • Pick Disease

  • Pick'S Disease

  • Pick Disease Of The Brain

  • Lobar Atrophy Of Brain

  • Dementia With Lobar Atrophy And Neuronal Cytoplasmic Inclusions

  • Behavioral Variant Of Frontotemporal Dementia

  • Dementia In Pick'S Disease

  • Lobar Atrophy Of The Brain

  • Bvftd

  • Bv-Ftd

  • PIDB

  • Picks Disease
Chromosome 1p36 Deletion Syndrome

  • 1p36 Deletion Syndrome

  • Deletion 1p36

  • Monosomy 1p36

  • Subtelomeric 1p36 Deletion

  • Monosomy 1p36 Syndrome

  • Distal Monosomy 1p36

  • Del(1)(P36)

  • Deletion 1pter

  • Monosomy 1pter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS10417 PHF13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta PHF13 VGNC VGNC:104232
Rattus norvegicus PHF13 RGD RGD:1308145
Bos taurus PHF13 VGNC VGNC:32815
Canis familiaris PHF13 VGNC VGNC:59030
Felis catus PHF13 VGNC VGNC:107599
Mus musculus PHF13 MGD MGI:2446217
Others PHF13 NCBI