2. Gene
  3. BNIPL - BCL2 interacting protein like Gene

BNIPL - BCL2 interacting protein like Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as BNIPS; PP753; BNIP-S; BNIPL1; BNIPL2; BNIPL-1; BNIPL-2; BNIP-Sbeta; BNIP-Salpha

Gene ID: 149428 | Gene type: protein coding

About BNIPL

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:151,036,586-151,047,720 (from NCBI)

This gene has 7 transcripts (splice variants), 236 orthologues and 3 paralogues. Biased expression in skin (RPKM 64.5), esophagus (RPKM 30.1) and 1 other tissue.

Summary

The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

BNIPL Products(2)

mRNA Protein Name
NM_001159642.2 NP_001153114.1 bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein isoform b
NM_138278.4 NP_612122.2 bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein isoform a

BNIPL Protein Structure

BNIP2

BNIP2: Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 (83 - 211)

CRAL_TRIO_2

CRAL_TRIO_2: Divergent CRAL/TRIO domain (213 - 349)

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  • 357 a.a.
Protein Preferred Names Protein Names

bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein

BCL2/adenovirus E1B 19kD interacting protein like

Related Diseases

Diseases Alias
Nephronophthisis 3

NPHP3

Nph3

Adolescent Nephronophthisis

Nephronophthisis, Type 3
Verrucous Papilloma
Cerebellopontine Angle Tumor

Cerebellopontine Angle Tumour

Neoplasm Of The Cerebellopontine Angle
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01566 BNIPL Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus BNIPL RGD RGD:1309478
Bos taurus BNIPL VGNC VGNC:26535
Canis familiaris BNIPL VGNC VGNC:38494
Mus musculus BNIPL MGD MGI:2384749
Macaca mulatta BNIPL VGNC VGNC:70329
Felis catus BNIPL VGNC VGNC:80148