H1f0 - H1.0 linker histone Gene
Also Known as H1-0; H1fv; H1(0); D130017D06Rik
Species: Mus musculus
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
H1f0 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_008197.3 | NP_032223.2 | histone H1.0 |
| NM_008197.3 | NP_032223.2 | histone H1.0 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables DNA binding |
EXP
EXP: Inferred from Experiment
|
11584004 | MGI |
| enables double-stranded DNA binding |
IMP
IMP: Inferred from mutant phenotype
|
16006555 | MGI |
| enables minor groove of adenine-thymine-rich DNA binding |
IMP
IMP: Inferred from mutant phenotype
|
11413144 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| NOT located in nucleolus |
IDA
IDA: Inferred from direct assay
|
22868987 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
9067599 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
histone H1.0 |
|
|