H3f3b - H3.3 histone B Gene

Also Known as H3-3a; H3-3b; H3.3B; 9430068D06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15081

Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a replication-independent histone that is a member of the histone H3 family. [provided by RefSeq, Nov 2015]

H3f3b Products (2)

mRNA Protein Name
NM_008211.3 NP_032237.1 histone H3.3
NM_008211.3 NP_032237.1 histone H3.3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell population proliferation IGI
IGI: Inferred from genetic interaction
26159997 MGI
acts upstream of or within embryo implantation IMP
IMP: Inferred from mutant phenotype
7534202 MGI
acts upstream of or within male gonad development IMP
IMP: Inferred from mutant phenotype
25675407 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
25675407 MGI
acts upstream of or within muscle cell differentiation IGI
IGI: Inferred from genetic interaction
22705305 MGI
acts upstream of or within negative regulation of chromosome condensation IGI
IGI: Inferred from genetic interaction
23903189 MGI
acts upstream of or within nucleus organization IMP
IMP: Inferred from mutant phenotype
23570311 MGI
acts upstream of or within oogenesis IGI
IGI: Inferred from genetic interaction
25675407 MGI
acts upstream of or within osteoblast differentiation IGI
IGI: Inferred from genetic interaction
22705305 MGI
acts upstream of or within pericentric heterochromatin formation IGI
IGI: Inferred from genetic interaction
26159997 MGI
acts upstream of or within regulation of centromere complex assembly IMP
IMP: Inferred from mutant phenotype
23570311 MGI
acts upstream of or within single fertilization IMP
IMP: Inferred from mutant phenotype
25675407 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
25675407 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
25675407 MGI
acts upstream of or within subtelomeric heterochromatin formation IGI
IGI: Inferred from genetic interaction
26159997 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
23570311 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone H3.3

  • H3 histone, family 3B

  • H3L-like histone

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05962 H3-3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown