Hsd17b10 - hydroxysteroid (17-beta) dehydrogenase 10 Gene

Also Known as Ads9; ERAB; MHBD; Hadh2; 17bHSD10

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15108

Summary

Predicted to enable several functions, including amyloid-beta binding activity; Estrogen receptor binding activity; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in several processes, including carboxylic acid metabolic process; cellular hormone metabolic process; and mitochondrial tRNA processing. Predicted to act upstream of or within steroid metabolic process and tRNA processing. Located in endoplasmic reticulum and mitochondrial nucleoid. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in chromosome Xp11.22 duplication syndrome; pheochromocytoma; and syndromic X-linked intellectual disability type 10. Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10). [provided by Alliance of Genome Resources, Apr 2022]

Hsd17b10 Products (1)

mRNA Protein Name
NM_016763.2 NP_058043.3 3-hydroxyacyl-CoA dehydrogenase type-2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
15962010 MGI
located in mitochondrial nucleoid IDA
IDA: Inferred from direct assay
24703694 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
14651853 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3-hydroxyacyl-CoA dehydrogenase type-2

  • 17-beta-HSD 10

  • 17-beta-estradiol 17-dehydrogenase

  • 17-beta-hydroxysteroid dehydrogenase 10

  • 2-methyl-3-hydroxybutyryl-CoA dehydrogenase

  • 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))

  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase

  • 3-hydroxyacyl-C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06390 HSD17B10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd17b10 NCBI NCBI:3028