ZNF385B - zinc finger protein 385B Gene

Also Known as ZNF533

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 151126

About ZNF385B

Cytogenetic location: 2q31.2-q31.3 Genomic coordinates (GRCh38): 2:179,441,982-179,861,612 (from NCBI)

This gene has 13 transcripts (splice variants), 225 orthologues and 9 paralogues. Broad expression in lung (RPKM 1.7), heart (RPKM 1.4) and 14 other tissues.

Summary

Enables p53 binding activity. Involved in intrinsic apoptotic signaling pathway by p53 class mediator. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF385B Products (14)

mRNA Protein Name
NM_001113397.2 NP_001106868.1 zinc finger protein 385B isoform 2
NM_001113398.3 NP_001106869.1 zinc finger protein 385B isoform 3
NM_001282725.3 NP_001269654.1 zinc finger protein 385B isoform 3
NM_001352808.2 NP_001339737.1 zinc finger protein 385B isoform 1
NM_001352809.2 NP_001339738.1 zinc finger protein 385B isoform 4
NM_001352810.2 NP_001339739.1 zinc finger protein 385B isoform 5
NM_001352811.2 NP_001339740.1 zinc finger protein 385B isoform 6
NM_001352812.2 NP_001339741.1 zinc finger protein 385B isoform 7
NM_001352813.2 NP_001339742.1 zinc finger protein 385B isoform 3
NM_001352814.2 NP_001339743.1 zinc finger protein 385B isoform 3
NM_001352815.1 NP_001339744.1 zinc finger protein 385B isoform 3
NM_001352816.2 NP_001339745.1 zinc finger protein 385B isoform 8
NM_001352817.1 NP_001339746.1 zinc finger protein 385B isoform 9
NM_152520.6 NP_689733.4 zinc finger protein 385B isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables p53 binding IPI
IPI: Inferred from physical interaction
22945289 GOA
Biological Process GO Annotation Evidence References Source
involved in intrinsic apoptotic signaling pathway by p53 class mediator IDA
IDA: Inferred from direct assay
22945289 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
22945289 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF385B Protein Structure

zf-met

zf-met: Zinc-finger of C2H2 type (35 - 58)

zf-met

zf-met: Zinc-finger of C2H2 type (158 - 181)

zf-met

zf-met: Zinc-finger of C2H2 type (285 - 309)

zf-met

zf-met: Zinc-finger of C2H2 type (348 - 372)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 471 a.a.
Protein Preferred Names Protein Names

zinc finger protein 385B

  • zinc finger protein 533

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16134 ZNF385B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ZNF385B RGD RGD:1311181
Bos taurus ZNF385B VGNC VGNC:37264
Canis familiaris ZNF385B VGNC VGNC:48715
Mus musculus ZNF385B MGD MGI:2444734
Felis catus ZNF385B VGNC VGNC:67301
Macaca mulatta ZNF385B VGNC VGNC:79600
Others ZNF385B NCBI