2. Gene
  3. Hba-a1 - hemoglobin alpha, adult chain 1 Gene

Hba-a1 - hemoglobin alpha, adult chain 1 Gene

  • Gene
  • Protein
Mus musculus

Also known as Hba; Hba1; Hbat1

Gene ID: 15122 | Gene type: protein coding

About Hba-a1

Summary

Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Acts upstream of or within several processes, including erythrocyte development; in utero embryonic development; and response to stilbenoid. Located in myelin sheath. Is expressed in several structures, including blood vessel; early conceptus; hematopoietic system; liver; and visceral pericardium. Human ortholog(s) of this gene implicated in Heinz body anemia; alpha thalassemia; familial erythrocytosis 7; and Hemoglobin H disease. Orthologous to human HBA2 (Hemoglobin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Hba-a1 Products(1)

mRNA Protein Name
NM_008218.2 NP_032244.2 hemoglobin subunit alpha
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within erythrocyte development IGI
IGI: Inferred from genetic interaction
7550311 MGI
acts upstream of or within in utero embryonic development IGI
IGI: Inferred from genetic interaction
7550311 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
involved in response to stilbenoid IEP
IEP: Inferred from expression pattern
17086191 MGI
Cellular Component GO Annotation Evidence Reference Source
part of hemoglobin complex IPI
IPI: Inferred from physical interaction
33830076 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hemoglobin subunit alpha

alpha 1 globin

alpha globin 1

alpha-globin

haemaglobin alpha 1

hemoglobin alpha chain