Hbb-y - hemoglobin Y, beta-like embryonic chain Gene

Also Known as Ey; Hby

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15135

Summary

Predicted to enable several functions, including heme binding activity; Hemoglobin alpha binding activity; and oxygen carrier activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be part of haptoglobin-hemoglobin complex and Hemoglobin complex. Is expressed in several structures, including blood; extraembryonic component; genitourinary system; limb; and nervous system. Human ortholog(s) of this gene implicated in sickle cell anemia. Orthologous to human HBE1 (Hemoglobin subunit epsilon 1). [provided by Alliance of Genome Resources, Apr 2022]

Hbb-y Products (2)

mRNA Protein Name
NM_008221.4 NP_032247.1 hemoglobin subunit epsilon-Y2
NM_008221.4 NP_032247.1 hemoglobin subunit epsilon-Y2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
17077320 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17077320 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hemoglobin subunit epsilon-Y2

  • epsilon Y globin

  • epsilon-Y2-globin

  • hemoglobin epsilon-Y2 chain