1. Gene
  2. EFHB - EF-hand domain family member B Gene

EFHB - EF-hand domain family member B Gene

Homo sapiens

Also known as CFAP21

Gene ID: 151651 | Gene type: protein coding

About EFHB

This gene has 7 transcripts (splice variants), 139 orthologues and 2 paralogues. Biased expression in testis (RPKM 7.6), lung (RPKM 1.1) and 1 other tissue.

Summary

Enables calcium ion sensor activity. Involved in negative regulation of protein binding activity; regulation of calcineurin-NFAT signaling cascade; and regulation of store-operated calcium entry. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

EFHB Products(2)

mRNA Protein Name
NM_001330688.2 NP_001317617.1 EF-hand domain-containing family member B isoform 2
NM_144715.4 NP_653316.3 EF-hand domain-containing family member B isoform 1

EFHB Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (567 - 625)

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  • 200
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  • 600
  • 833 a.a.
Protein Preferred Names Protein Names

EF-hand domain-containing family member B

cilia and flagella associated protein 21

Orthologs Information

Species Symbol Source ID
Canis familiaris EFHB VGNC VGNC:40222
Bos taurus EFHB VGNC VGNC:28350
Macaca mulatta EFHB VGNC VGNC:72118
Mus musculus EFHB MGD MGI:3045296
Felis catus EFHB VGNC VGNC:61745
Rattus norvegicus EFHB RGD RGD:1566407