Foxg1 - forkhead box G1 Gene

Also Known as Bf1; BF-1; Hfh9; Hfhbf1; 2900064B05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15228

Summary

Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including generation of neurons; inner ear morphogenesis; and regulation of neuron differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; embryo endoderm; hemolymphoid system; and sensory organ. Used to study Rett syndrome. Orthologous to human FOXG1 (forkhead box G1). [provided by Alliance of Genome Resources, Apr 2022]

Foxg1 Products (2)

mRNA Protein Name
NM_001160112.1 NP_001153584.1 forkhead box protein G1
NM_008241.2 NP_032267.1 forkhead box protein G1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15084259 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
23332764 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axon midline choice point recognition IMP
IMP: Inferred from mutant phenotype
15240555 MGI
acts upstream of cell cycle IMP
IMP: Inferred from mutant phenotype
15893304 MGI
acts upstream of or within cell morphogenesis involved in neuron differentiation IMP
IMP: Inferred from mutant phenotype
16691564 MGI
acts upstream of or within central nervous system neuron development IMP
IMP: Inferred from mutant phenotype
16680166 MGI
acts upstream of or within cerebral cortex development IDA
IDA: Inferred from direct assay
22726835 MGI
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: Inferred from mutant phenotype
14566948 MGI
acts upstream of or within forebrain development IMP
IMP: Inferred from mutant phenotype
7605629 MGI
acts upstream of or within inner ear morphogenesis IGI
IGI: Inferred from genetic interaction
16691564 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: Inferred from mutant phenotype
16691564 MGI
acts upstream of or within negative regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
7605629 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16314515 MGI
acts upstream of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
15893304 MGI
acts upstream of or within neurogenesis IDA
IDA: Inferred from direct assay
18184563 MGI
acts upstream of neuron differentiation IMP
IMP: Inferred from mutant phenotype
7605629 MGI
acts upstream of or within neuron fate determination IDA
IDA: Inferred from direct assay
22726835 MGI
acts upstream of or within positive regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
15893304 MGI
acts upstream of or within positive regulation of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
15893304 MGI
acts upstream of or within positive regulation of neuron differentiation IGI
IGI: Inferred from genetic interaction
16314515 MGI
acts upstream of or within pyramidal neuron migration to cerebral cortex IDA
IDA: Inferred from direct assay
22726835 MGI
acts upstream of or within regulation of cell cycle IDA
IDA: Inferred from direct assay
22726835 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
22726835 MGI
acts upstream of or within regulation of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
12151532 MGI
acts upstream of or within regulation of neural precursor cell proliferation IGI
IGI: Inferred from genetic interaction
22516202 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
16314515 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

forkhead box protein G1

  • HNF-3/forkhead homolog, brain factor 1

  • forkhead-related protein FKHL1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N3610 Coclaurine Antagonist 98.97% Unkown
HY-RS05051 FOXG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxg1 NCBI NCBI:2290