Hmg20b - high mobility group 20B Gene

Also Known as Hmgx2; BRAF35; Hmgxb2; Smarce1r

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15353

Summary

Predicted to enable four-way junction DNA binding activity. Acts upstream of or within negative regulation of protein sumoylation; positive regulation of neuron differentiation; and skeletal muscle cell differentiation. Predicted to be located in condensed nuclear chromosome and nuclear body. Predicted to be part of BRCA2-BRAF35 complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; foregut; and genitourinary system. Orthologous to human HMG20B (high mobility group 20B). [provided by Alliance of Genome Resources, Apr 2022]

Hmg20b Products (3)

mRNA Protein Name
NM_001163165.1 NP_001156637.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
NM_001163166.1 NP_001156638.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
NM_010440.3 NP_034570.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of protein sumoylation IDA
IDA: Inferred from direct assay
22570500 MGI
acts upstream of or within positive regulation of neuron differentiation IGI
IGI: Inferred from genetic interaction
22570500 MGI
acts upstream of protein sumoylation IDA
IDA: Inferred from direct assay
22570500 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
22147266 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

  • BRCA2-associated factor 35

  • HMG box-containing protein 20B

  • SMARCE1-related protein

  • high mobility group 20 B

  • high mobility group protein 20 B

  • structural DNA-binding protein BRAF35

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06229 HMG20B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hmg20b NCBI NCBI:10362