Hmx3 - H6 homeobox 3 Gene

Also Known as Nkx5-1; Nkx5.1; Nkx-5.1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15373

Summary

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in ear development. Acts upstream of or within several processes, including embryo implantation; maternal process involved in female pregnancy; and neuromuscular process controlling balance. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; branchial arch; female reproductive system; nervous system; and sensory organ. Orthologous to human HMX3 (H6 family homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Hmx3 Products (1)

mRNA Protein Name
NM_008257.3 NP_032283.3 homeobox protein HMX3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10206974 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
10206974 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10206974 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IGI
IGI: Inferred from genetic interaction
15363417 MGI
involved in ear development IMP
IMP: Inferred from mutant phenotype
14695375 MGI
acts upstream of or within embryo implantation IMP
IMP: Inferred from mutant phenotype
9435283 MGI
acts upstream of or within inner ear morphogenesis IGI
IGI: Inferred from genetic interaction
15363417 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: Inferred from mutant phenotype
9435283 MGI
acts upstream of or within maternal process involved in female pregnancy IMP
IMP: Inferred from mutant phenotype
9435283 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: Inferred from mutant phenotype
9435283 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein HMX3

  • H6 homeo box 3

  • homeobox protein H6 family member 3

  • homeobox protein Nkx-5.1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06254 HMX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hmx3 NCBI NCBI:340784