Hnrnpa1 - heterogeneous nuclear ribonucleoprotein A1 Gene

Also Known as Hdp; HDP-1; Hnrpa1; hnRNP A1; hnrnp-A1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15382

Summary

Predicted to enable identical protein binding activity; nucleic acid binding activity; and protein domain specific binding activity. Acts upstream of or within alternative mRNA splicing, via spliceosome. Located in nucleus. Is expressed in 1-cell stage embryo; central nervous system; sensory organ; thymus; and tooth. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 20; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3; and tropical spastic paraparesis. Orthologous to human HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1) and HNRNPA1L2 (heterogeneous nuclear ribonucleoprotein A1 like 2). [provided by Alliance of Genome Resources, Apr 2022]

Hnrnpa1 Products (2)

mRNA Protein Name
NM_001039129.5 NP_001034218.1 heterogeneous nuclear ribonucleoprotein A1 isoform b
NM_010447.6 NP_034577.1 heterogeneous nuclear ribonucleoprotein A1 isoform a

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within RNA splicing IDA
IDA: Inferred from direct assay
15798186 MGI
acts upstream of or within alternative mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
15798186 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
15615787 MGI
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heterogeneous nuclear ribonucleoprotein A1

  • helix-destabilizing protein

  • hnRNP core protein A1

  • single-strand-binding protein

  • topoisomerase-inhibitor suppressed

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06261 HNRNPA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19543 Hnrnpa1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26039 Hnrnpa1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hnrnpa1 NCBI NCBI:3178