NKAIN2 - sodium/potassium transporting ATPase interacting 2 Gene

Homo sapiens

Also known as TCBA; TCBA1; FAM77B; NKAIP2

Gene ID: 154215 | Gene type: protein coding

About NKAIN2

Cytogenetic location: 6q22.31 Genomic coordinates (GRCh38): 6:123,803,865-124,825,640 (from NCBI)

This gene has 6 transcripts (splice variants), 189 orthologues and 3 paralogues. Biased expression in brain (RPKM 16.9) and heart (RPKM 0.4).

Summary

This gene encodes a transmembrane protein that interacts with the beta subunit of a sodium/potassium-transporting ATPase. A chromosomal translocation involving this gene is a cause of lymphoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

NKAIN2 Products(5)

mRNA	Protein	Name
NM_001040214.3	NP_001035304.1	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 isoform 1
NM_001300737.2	NP_001287666.1	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 isoform 3
NM_001300738.2	NP_001287667.1	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 isoform 4
NM_001300740.1	NP_001287669.1	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 isoform 5
NM_153355.5	NP_699186.2	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 isoform 2

NKAIN2 Protein Structure

NKAIN

0
100
208 a.a.

Protein Preferred Names

Protein Names

sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2

Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 2

Related Diseases

Diseases

Alias

Lymphoma

Lymphoid Cancer	Lymphomas
Lymphoid Cancers	Lymphoid Neoplasm
Lymphoma Nos	Nhl - [Non-Hodgkin Lymphoma]
Non-Hodgkin Lymphoma	Non-Hodgkin Lymphoma, Nos
Non-Hodgkin Malignant Lymphoma Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09312	NKAIN2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	NKAIN2	VGNC	VGNC:97528
Macaca mulatta	NKAIN2	VGNC	VGNC:75188
Rattus norvegicus	NKAIN2	RGD	RGD:7740967
Mus musculus	NKAIN2	MGD	MGI:1923447

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