1. Gene
  2. Hoxd11 - homeobox D11 Gene

Hoxd11 - homeobox D11 Gene

Mus musculus

Also known as Hox-4.6; Hox-5.4; Hox-5.5; E230017H14Rik

Gene ID: 15431 | Gene type: protein coding

About Hoxd11

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; kidney development; and regionalization. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; limb; nervous system; and skin. Orthologous to human HOXD11 (homeobox D11). [provided by Alliance of Genome Resources, Apr 2022]

Hoxd11 Products(1)

mRNA Protein Name
NM_008273.2 NP_032299.1 homeobox protein Hox-D11
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
12869760 MGI
acts upstream of or within branching involved in ureteric bud morphogenesis IGI
IGI: Inferred from genetic interaction
11493536 MGI
acts upstream of or within cartilage development involved in endochondral bone morphogenesis IGI
IGI: Inferred from genetic interaction
14668414 MGI
acts upstream of cell development IGI
IGI: Inferred from genetic interaction
14668414 MGI
acts upstream of chondrocyte development IGI
IGI: Inferred from genetic interaction
14668414 MGI
acts upstream of chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
14668414 MGI
acts upstream of or within developmental growth IGI
IGI: Inferred from genetic interaction
14668414 MGI
acts upstream of or within dorsal/ventral pattern formation IGI
IGI: Inferred from genetic interaction
11493536 MGI
acts upstream of or within embryonic digit morphogenesis IGI
IGI: Inferred from genetic interaction
8900279 MGI
acts upstream of or within embryonic forelimb morphogenesis IGI
IGI: Inferred from genetic interaction
22916278 MGI
acts upstream of or within embryonic limb morphogenesis IGI
IGI: Inferred from genetic interaction
14668414 MGI
acts upstream of or within embryonic skeletal joint morphogenesis IGI
IGI: Inferred from genetic interaction
20978074 MGI
acts upstream of or within metanephros development IGI
IGI: Inferred from genetic interaction
12050119 MGI
acts upstream of or within organ induction IGI
IGI: Inferred from genetic interaction
12050119 MGI
acts upstream of or within pattern specification process IGI
IGI: Inferred from genetic interaction
8900279 MGI
acts upstream of or within positive regulation of chondrocyte development IGI
IGI: Inferred from genetic interaction
14668414 MGI
acts upstream of or within positive regulation of chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
14668414 MGI
acts upstream of or within proximal/distal pattern formation IGI
IGI: Inferred from genetic interaction
12869760 MGI
acts upstream of or within regulation of chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
22916278 MGI
acts upstream of or within regulation of gene expression IGI
IGI: Inferred from genetic interaction
23760953 MGI
acts upstream of or within single fertilization IGI
IGI: Inferred from genetic interaction
23760953 MGI
acts upstream of or within skeletal system development IGI
IGI: Inferred from genetic interaction
12869760 MGI
acts upstream of or within skeletal system development IMP
IMP: Inferred from mutant phenotype
7925020 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-D11

homeo box D11

homeobox protein Hox-4.6

homeobox protein Hox-5.5

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxd11 NCBI NCBI:3237