Hoxd12 - homeobox D12 Gene
Also Known as Hox-4.7; Hox-5.6
Species: Mus musculus
Summary
Predicted to enable sequence-specific double-stranded DNA binding activity. Acts upstream of or within embryonic digit morphogenesis; pattern specification process; and skeletal system development. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; limb; and limb bud. Human ortholog(s) of this gene implicated in clubfoot. Orthologous to human HOXD12 (homeobox D12). [provided by Alliance of Genome Resources, Apr 2022]
Hoxd12 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_008274.3 | NP_032300.2 | homeobox protein Hox-D12 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
9343407 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within embryonic digit morphogenesis |
IGI
IGI: Inferred from genetic interaction
|
8900279 | MGI |
| acts upstream of or within pattern specification process |
IGI
IGI: Inferred from genetic interaction
|
8900279 | MGI |
| acts upstream of or within skeletal system development |
IMP
IMP: Inferred from mutant phenotype
|
8620844 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of transcription regulator complex |
IDA
IDA: Inferred from direct assay
|
9343407 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
homeobox protein Hox-D12 |
|
|