2. Gene
  3. Hoxd12 - homeobox D12 Gene

Hoxd12 - homeobox D12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hox-4.7; Hox-5.6

Gene ID: 15432 | Gene type: protein coding

About Hoxd12

Summary

Predicted to enable sequence-specific double-stranded DNA binding activity. Acts upstream of or within embryonic digit morphogenesis; pattern specification process; and skeletal system development. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; limb; and limb bud. Human ortholog(s) of this gene implicated in clubfoot. Orthologous to human HOXD12 (homeobox D12). [provided by Alliance of Genome Resources, Apr 2022]

Hoxd12 Products(1)

mRNA Protein Name
NM_008274.3 NP_032300.2 homeobox protein Hox-D12
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
9343407 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within embryonic digit morphogenesis IGI
IGI: Inferred from genetic interaction
8900279 MGI
acts upstream of or within pattern specification process IGI
IGI: Inferred from genetic interaction
8900279 MGI
acts upstream of or within skeletal system development IMP
IMP: Inferred from mutant phenotype
8620844 MGI
Cellular Component GO Annotation Evidence Reference Source
part of transcription regulator complex IDA
IDA: Inferred from direct assay
9343407 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-D12

homeo box D12

homeobox protein Hox-4.7

homeobox protein Hox-5.6

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06325 HOXD12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxd12 NCBI NCBI:3238