2. Gene
  3. Hoxd8 - homeobox D8 Gene

Hoxd8 - homeobox D8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hox-4.3; Hox-5.4; 4921540P06Rik

Gene ID: 15437 | Gene type: protein coding

About Hoxd8

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within anterior/posterior pattern specification; negative regulation of transcription by RNA polymerase II; and skeletal system morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; hindlimb bud; limb; and nervous system. Orthologous to human HOXD8 (homeobox D8). [provided by Alliance of Genome Resources, Apr 2022]

Hoxd8 Products(3)

mRNA Protein Name
NM_001290730.2 NP_001277659.1 homeobox protein Hox-D8 isoform b
NM_001290731.2 NP_001277660.1 homeobox protein Hox-D8 isoform c
NM_008276.4 NP_032302.2 homeobox protein Hox-D8 isoform a
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
11311170 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
11311170 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
1756725 MGI
acts upstream of or within skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
11311170 MGI
acts upstream of or within skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
11311170 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-D8

homeo box D8

homeobox protein Hox-4.3

homeobox protein Hox-5.4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06329 HOXD8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxd8 NCBI NCBI:3234