2. Gene
  3. Cldn16 - claudin 16 Gene

Cldn16 - claudin 16 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pcln1

Gene ID: 155268 | Gene type: protein coding

About Cldn16

Summary

Predicted to enable identical protein binding activity. Involved in positive regulation of calcium ion transport and transepithelial transport. Located in bicellular tight junction. Used to study hypertension. Human ortholog(s) of this gene implicated in renal hypomagnesemia 3 and renal tubular transport disease. Orthologous to human CLDN16 (Claudin 16). [provided by Alliance of Genome Resources, Apr 2022]

Cldn16 Products(1)

mRNA Protein Name
NM_131905.2 NP_571980.2 claudin-16
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15496416 RGD
Biological Process GO Annotation Evidence Reference Source
involved in paracellular transport IDA
IDA: Inferred from direct assay
15496416 RGD
involved in positive regulation of calcium ion transport IDA
IDA: Inferred from direct assay
15496416 RGD
involved in transepithelial transport IDA
IDA: Inferred from direct assay
15496416 RGD
Cellular Component GO Annotation Evidence Reference Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
15496416 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

claudin-16

paracellin-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02767 CLDN16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cldn16 NCBI NCBI:10686