2. Gene
  3. Hey2 - hes-related family bHLH transcription factor with YRPW motif 2 Gene

Hey2 - hes-related family bHLH transcription factor with YRPW motif 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Herp1

Gene ID: 155430 | Gene type: protein coding

About Hey2

Summary

Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; histone deacetylase binding activity; and identical protein binding activity. Involved in Notch signaling pathway and heart development. Located in nucleus. Orthologous to human HEY2 (hes related family bHLH transcription factor with YRPW motif 2). [provided by Alliance of Genome Resources, Apr 2022]

Hey2 Products(1)

mRNA Protein Name
NM_130417.1 NP_569101.1 hairy/enhancer-of-split related with YRPW motif protein 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables RNA polymerase II-specific DNA-binding transcription factor binding IDA
IDA: Inferred from direct assay
16151017 RGD
Biological Process GO Annotation Evidence Reference Source
involved in Notch signaling pathway IDA
IDA: Inferred from direct assay
11741889 RGD
involved in heart development IEP
IEP: Inferred from expression pattern
10692439 RGD
involved in negative regulation of cardiac vascular smooth muscle cell differentiation IDA
IDA: Inferred from direct assay
16151017 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16151017 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hairy/enhancer-of-split related with YRPW motif protein 2

hairy/enhancer-of-split related with YRPW motif 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06147 HEY2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hey2 NCBI NCBI:23493