2. Gene
  3. CYP2F1 - cytochrome P450 family 2 subfamily F member 1 Gene

CYP2F1 - cytochrome P450 family 2 subfamily F member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as C2F1; CYP2F; CYPIIF1

Gene ID: 1572 | Gene type: protein coding

About CYP2F1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,114,432-41,128,381 (from NCBI)

This gene has 6 transcripts (splice variants), 78 orthologues and 15 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of Cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

CYP2F1 Products(1)

mRNA Protein Name
NM_000774.5 NP_000765.2 cytochrome P450 2F1 precursor

CYP2F1 Protein Structure

p450

p450: Cytochrome P450 (31 - 488)

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  • 491 a.a.
Protein Preferred Names Protein Names

cytochrome P450 2F1

cytochrome P450, family 2, subfamily F, polypeptide 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03464 CYP2F1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CYP2F1 VGNC VGNC:103640
Felis catus CYP2F1 VGNC VGNC:103485
Canis familiaris CYP2F1 VGNC VGNC:50386
Rattus norvegicus CYP2F1 RGD RGD:2476
Bos taurus CYP2F1 VGNC VGNC:110257
Mus musculus CYP2F1 MGD MGI:88608