KCNU1 - potassium calcium-activated channel subfamily U member 1 Gene
Also Known as KCa5; Slo3; KCNMC1; KCa5.1; Kcnma3; SPGF79
Species: Homo sapiens (human)
Summary
This gene encodes a member of the Potassium Channel family of proteins. The encoded voltage-gated ion channel allows the outward flow of potassium ions during plasma membrane hyperpolarization in sperm. Opening of this channel may be regulated by calcium ion levels. Homozygous knockout mice that lack the related mouse gene exhibit male sterility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
KCNU1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| XM_011544426.3 | XP_011542728.1 | potassium channel subfamily U member 1 isoform X3 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables potassium channel activity |
IMP
IMP: Inferred from mutant phenotype
|
34980136 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in potassium ion transmembrane transport |
IDA
IDA: Inferred from direct assay
|
23129643 | GOA |
| involved in reproductive process |
IMP
IMP: Inferred from mutant phenotype
|
34980136 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in sperm flagellum |
IDA
IDA: Inferred from direct assay
|
24670955 | GOA |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
potassium channel subfamily U member 1 |
|
|