1. Gene
  2. KCNU1 - potassium calcium-activated channel subfamily U member 1 Gene

KCNU1 - potassium calcium-activated channel subfamily U member 1 Gene

Homo sapiens (human)

Also known as KCa5; Slo3; KCNMC1; KCa5.1; Kcnma3; SPGF79

Gene ID: 157855 | Gene type: protein coding

About KCNU1

Summary

This gene encodes a member of the Potassium Channel family of proteins. The encoded voltage-gated ion channel allows the outward flow of potassium ions during plasma membrane hyperpolarization in sperm. Opening of this channel may be regulated by calcium ion levels. Homozygous knockout mice that lack the related mouse gene exhibit male sterility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

KCNU1 Products(1)

mRNA Protein Name
XM_011544426.3 XP_011542728.1 potassium channel subfamily U member 1 isoform X3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables potassium channel activity IMP
IMP: Inferred from mutant phenotype
34980136 GOA
Biological Process GO Annotation Evidence Reference Source
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
23129643 GOA
involved in reproductive process IMP
IMP: Inferred from mutant phenotype
34980136 GOA
Cellular Component GO Annotation Evidence Reference Source
located in sperm flagellum IDA
IDA: Inferred from direct assay
24670955 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium channel subfamily U member 1

Calcium-activated potassium channel subunit alpha-3

Calcium-activated potassium channel, subfamily M subunit alpha-3

Slowpoke homolog 3

potassium channel, subfamily U, member 1