ARHGAP36 - Rho GTPase activating protein 36 Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 158763

About ARHGAP36

Cytogenetic location: Xq26.1 Genomic coordinates (GRCh38): X:131,058,346-131,089,885 (from NCBI)

This gene has 6 transcripts (splice variants), 187 orthologues and 1 paralogue. Restricted expression toward adrenal (RPKM 54.0).

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in regulation of catalytic activity and signal transduction. [provided by Alliance of Genome Resources, Apr 2022]

ARHGAP36 Products (3)

mRNA	Protein	Name
NM_001282607.2	NP_001269536.1	rho GTPase-activating protein 36 isoform 2
NM_001330651.1	NP_001317580.1	rho GTPase-activating protein 36 isoform 3
NM_144967.4	NP_659404.2	rho GTPase-activating protein 36 isoform 1 precursor

ARHGAP36 Protein Structure

RhoGAP

0
100
200
300
400
500
547 a.a.

Protein Preferred Names	Protein Names
rho GTPase-activating protein 36

Related Diseases

Diseases	Alias
Hypothyroidism, Central, With Testicular Enlargement	X-Linked Central Congenital Hypothyroidism With Late-Onset Testicular Enlargement CHTE Hypothyroidism, Central, And Testicular Enlargement Igsf1 Deficiency Syndrome X-Linked Central Congenital Hypothyroidism With Late-Onset Macroorchidism Central Hypothyroidism And Testicular Enlargement Hypothyroidism, Central, Testicular Enlargement
Cns Neuroblastoma With Foxr2 Activation	Central Nervous System Neuroblastoma With Foxr2 Activation Cns Nb-Foxr2 Cns Neuroblastoma, Foxr2-Activated
Central Nervous System Neuroblastoma
Central Nervous System Germ Cell Tumor	Central Nervous System Germ Cell Tumour Germ Cell Tumor Of The Cns Germ Cell Tumour Of The Cns

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00934	ARHGAP36 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ARHGAP36	VGNC	VGNC:38061
Bos taurus	ARHGAP36	VGNC	VGNC:26093
Rattus norvegicus	ARHGAP36	RGD	RGD:1565967
Felis catus	ARHGAP36	VGNC	VGNC:59891
Macaca mulatta	ARHGAP36	VGNC	VGNC:69917
Mus musculus	ARHGAP36	MGD	MGI:1922654