Il12rb1 - interleukin 12 receptor, beta 1 Gene

Also Known as CD212; IL-12R[b]; IL-12R-beta-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16161

Summary

Contributes to cytokine binding activity. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in external side of plasma membrane. Part of interleukin-23 receptor complex. Is expressed in mandible; maxilla; orbito-sphenoid; rib; and testis. Human ortholog(s) of this gene implicated in immunodeficiency 30. Orthologous to human IL12RB1 (interleukin 12 receptor subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Il12rb1 Products (1)

mRNA Protein Name
NM_008353.3 NP_032379.2 interleukin-12 receptor subunit beta-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to cytokine binding IPI
IPI: Inferred from physical interaction
11114383 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within peptidyl-tyrosine phosphorylation IMP
IMP: Inferred from mutant phenotype
11489994 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
15220916 MGI
part of interleukin-23 receptor complex IDA
IDA: Inferred from direct assay
11114383 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-12 receptor subunit beta-1

  • IL-12 receptor beta component

  • IL-12 receptor subunit beta-1

  • IL-12R subunit beta-1

  • Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06683 IL12RB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174616 Human IL23R mRNA / Unkown
HY-174640 Human IL12RB1 mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il12rb1 NCBI NCBI:3594