ANKFN1 - ankyrin repeat and fibronectin type III domain containing 1 Gene
Species: Homo sapiens
About ANKFN1
This gene has 11 transcripts (splice variants) and 176 orthologues. Low expression observed in reference dataset.
Summary
Predicted to be involved in establishment of mitotic spindle orientation and regulation of establishment of bipolar cell polarity. Predicted to act upstream of or within behavioral fear response; equilibrioception; and locomotor rhythm. Predicted to be active in spindle. [provided by Alliance of Genome Resources, Apr 2022]
ANKFN1 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001365758.1 | NP_001352687.1 | ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform 1 |
| NM_001370326.1 | NP_001357255.1 | ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform 3 |
| NM_153228.3 | NP_694960.2 | ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform 2 |
ANKFN1 Protein Structure
Ank_4: Ankyrin repeats (many copies) (137 - 194)
fn3: Fibronectin type III domain (274 - 358)
- 0
- 200
- 400
- 600
- 763 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ankyrin repeat and fibronectin type-III domain-containing protein 1 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Cannabis Dependence |
|
|
| Hallucinogen Dependence |
|
|
| Proximal Symphalangism |
|
|
| Otosclerosis |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | ANKFN1 | VGNC | VGNC:37871 |
| Rattus norvegicus | ANKFN1 | RGD | RGD:7736477 |
| Mus musculus | ANKFN1 | MGD | MGI:2686021 |
| Macaca mulatta | ANKFN1 | VGNC | VGNC:69712 |
| Felis catus | ANKFN1 | VGNC | VGNC:98760 |
| Others | ANKFN1 | NCBI |