LEXM - lymphocyte expansion molecule Gene

Homo sapiens

Also known as LEM; C1orf177

Gene ID: 163747 | Gene type: protein coding

About LEXM

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:54,806,063-54,842,252 (from NCBI)

This gene has 2 transcripts (splice variants) and 109 orthologues. Biased expression in esophagus (RPKM 2.6), testis (RPKM 1.5) and 3 other tissues.

Summary

Predicted to enable mitochondrial ribosome binding activity. Predicted to act upstream of or within positive regulation of cell population proliferation and positive regulation of oxidative phosphorylation. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

LEXM Products(2)

mRNA	Protein	Name
NM_001110533.2	NP_001104003.1	lymphocyte expansion molecule isoform 2
NM_152607.3	NP_689820.2	lymphocyte expansion molecule isoform 1

Protein Preferred Names

Protein Names

lymphocyte expansion molecule

Related Diseases

Diseases

Alias

Emery-Dreifuss Muscular Dystrophy 1, X-Linked

EDMD1	Emd1
Muscular Dystrophy, Tardive, Dreifuss-Emery Type, With Contractures	X-Linked Emery-Dreifuss Muscular Dystrophy 1
Humeroperoneal Neuromuscular Disease	X-Linked Emery-Dreifuss Muscular Dystrophy
Scapuloperoneal Syndrome, X-Linked, Formerly	Humeroperoneal Neuromuscular Disease, Formerly
Scapuloperoneal Syndrome, X-Linked	Muscular Dystrophy Tardive Dreifuss-Emery Type With Contractures
Scapuloperoneal Syndrome X-Linked	X-Edmd
Dystrophy, Muscular, Emery-Dreifuss, Type 1, X-Linked

Emery-Dreifuss Muscular Dystrophy

Edmd	Emery-Dreifuss Syndrome
Muscular Dystrophy, Emery-Dreifuss	Humeroperoneal Neuromuscular Disease
Muscular Dystrophy, Tardive, Dreifuss-Emery Type, With Contractures	Scapuloperoneal Syndrome, X-Linked
Benign Scapuloperoneal Muscular Dystrophy With Early Contractures	Muscular Dystrophy, Emery-Dreifuss Type
Muscular Dystrophy Emery-Dreifuss	Dystrophy, Muscular, Emery-Dreifuss
Emd - [Emery-Dreifuss Muscular Dystrophy]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07600	LEXM Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	LEXM	RGD	RGD:1559493
Canis familiaris	LEXM	VGNC	VGNC:42644
Macaca mulatta	LEXM	VGNC	VGNC:74135
Mus musculus	LEXM	MGD	MGI:2681853
Felis catus	LEXM	VGNC	VGNC:63217
Bos taurus	LEXM	VGNC	VGNC:30848