Kcnab1 - potassium voltage-gated channel, shaker-related subfamily, beta member 1 Gene

Also Known as Akr8a8; Kvbeta1.1; mKv(beta)1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16497

Summary

Predicted to enable several functions, including NADPH binding activity; Potassium Channel regulator activity; and transmembrane transporter binding activity. Acts upstream of or within learning or memory and regulation of potassium ion transmembrane transporter activity. Predicted to be located in several cellular components, including axon; dendrite; and perikaryon. Predicted to be part of voltage-gated Potassium Channel complex. Predicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in brain; heart; reproductive system; and urinary system. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A regulatory beta subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Kcnab1 Products (4)

mRNA Protein Name
NM_001289450.2 NP_001276379.1 voltage-gated potassium channel subunit beta-1 isoform 2
NM_001357358.2 NP_001344287.1 voltage-gated potassium channel subunit beta-1 isoform 3
NM_001403872.1 NP_001390801.1 voltage-gated potassium channel subunit beta-1 isoform 4
NM_010597.6 NP_034727.3 voltage-gated potassium channel subunit beta-1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15662035 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within learning or memory IMP
IMP: Inferred from mutant phenotype
14511342 MGI
acts upstream of or within regulation of potassium ion transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
15662035 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-gated potassium channel subunit beta-1

  • K(+) channel subunit beta-1

  • voltage dependent potassium channel subunit beta-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07103 KCNAB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnab1 NCBI NCBI:7881