Kcnj5 - potassium inwardly-rectifying channel, subfamily J, member 5 Gene

Also known as CIR; GIRK4; KATP-1; Kir3.4

About Kcnj5

Summary

Predicted to enable inward rectifier Potassium Channel activity and voltage-gated Potassium Channel activity involved in atrial cardiac muscle cell action potential repolarization. Predicted to be involved in cardiac conduction; potassium ion import across plasma membrane; and regulation of ion transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in T-tubule and external side of plasma membrane. Predicted to be part of voltage-gated Potassium Channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; heart; intestine; liver lobe; and placenta. Human ortholog(s) of this gene implicated in atrial fibrillation; long QT syndrome 13; and primary hyperaldosteronism. Orthologous to human KCNJ5 (potassium inwardly rectifying channel subfamily J member 5). [provided by Alliance of Genome Resources, Apr 2022]