Kif1a - kinesin family member 1A Gene

Also Known as ATSV; Kns1; Gm1626; C630002N23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16560

Summary

Enables microtubule binding activity. Predicted to be involved in several processes, including interkinetic nuclear migration; regulation of dendritic spine morphogenesis; and transport along microtubule. Located in neuron projection and neuronal cell body. Is expressed in nervous system; sensory organ; testis; and urinary system. Used to study hereditary spastic paraplegia 30. Human ortholog(s) of this gene implicated in NESCAV syndrome; hereditary sensory neuropathy; hereditary sensory neuropathy type 2C; hereditary spastic paraplegia; and hereditary spastic paraplegia 30. Orthologous to human KIF1A (Kinesin family member 1A). [provided by Alliance of Genome Resources, Apr 2022]

Kif1a Products (6)

mRNA Protein Name
NM_001110315.3 NP_001103785.1 kinesin-like protein KIF1A isoform b
NM_001294149.2 NP_001281078.1 kinesin-like protein KIF1A isoform c
NM_001294150.2 NP_001281079.1 kinesin-like protein KIF1A isoform d
NM_001368847.2 NP_001355776.1 kinesin-like protein KIF1A isoform e
NM_001408925.1 NP_001395854.1 kinesin-like protein KIF1A isoform f
NM_008440.5 NP_032466.2 kinesin-like protein KIF1A isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
17360631 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
30808661 MGI
Biological Process GO Annotation Evidence References Source
involved in anterograde synaptic vesicle transport IDA
IDA: Inferred from direct assay
7539720 MGI
Cellular Component GO Annotation Evidence References Source
located in neuron projection IDA
IDA: Inferred from direct assay
17360631 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
17360631 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kinesin-like protein KIF1A

  • N-3 kinesin

  • axonal transporter of synaptic vesicles

  • kinesin heavy chain member 1A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07269 KIF1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kif1a NCBI NCBI:547