Lama3 - laminin, alpha 3 Gene

Also Known as [a]3B; Lama3B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16774

Summary

Predicted to enable Integrin binding activity. Predicted to be an extracellular matrix structural constituent. Predicted to be involved in several processes, including axon guidance; integrin-mediated signaling pathway; and morphogenesis of a polarized epithelium. Located in basement membrane. Part of laminin-5 complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Used to study junctional epidermolysis bullosa and junctional epidermolysis bullosa non-Herlitz type. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Orthologous to human LAMA3 (laminin subunit alpha 3). [provided by Alliance of Genome Resources, Apr 2022]

Lama3 Products (2)

mRNA Protein Name
NM_001347461.2 NP_001334390.1 laminin subunit alpha-3 isoform 3A precursor
NM_010680.2 NP_034810.1 laminin subunit alpha-3 isoform 3B precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
9264260 MGI
part of laminin-5 complex IDA
IDA: Inferred from direct assay
9264260 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

laminin subunit alpha-3

  • epiligrin subunit alpha

  • kalinin subunit alpha

  • laminin-5 subunit alpha

  • laminin-6 subunit alpha

  • laminin-7 subunit alpha

  • nicein subunit alpha

  • nicein, 150kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07499 LAMA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07500 LAMA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20050 Lama3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26554 Lama3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lama3 NCBI NCBI:3909