2. Gene
  3. Lbx1 - ladybird homeobox 1 Gene

Lbx1 - ladybird homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Lbx1h

Gene ID: 16814 | Gene type: protein coding

About Lbx1

Summary

Enables DNA-binding transcription factor activity. Acts upstream of or within several processes, including heart looping; negative regulation of neuron differentiation; and neuron differentiation. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart; skeletal musculature; and urinary system. Orthologous to human LBX1 (ladybird homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Lbx1 Products(1)

mRNA Protein Name
NM_010691.6 NP_034821.2 transcription factor LBX1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
15528197 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15528197 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
12522123 MGI
acts upstream of glutamatergic neuron differentiation IMP
IMP: Inferred from mutant phenotype
16234809 MGI
acts upstream of or within heart looping IMP
IMP: Inferred from mutant phenotype
12522123 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
12522123 MGI
acts upstream of or within negative regulation of glutamatergic neuron differentiation IMP
IMP: Inferred from mutant phenotype
16234809 MGI
acts upstream of or within neuron fate commitment IMP
IMP: Inferred from mutant phenotype
12062039 MGI
acts upstream of or within neuron fate determination IGI
IGI: Inferred from genetic interaction
16234809 MGI
acts upstream of or within neuron fate determination IMP
IMP: Inferred from mutant phenotype
16234809 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
15528197 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
12062038 MGI
acts upstream of or within spinal cord motor neuron differentiation IGI
IGI: Inferred from genetic interaction
15769945 MGI
Cellular Component GO Annotation Evidence Reference Source
part of transcription regulator complex IDA
IDA: Inferred from direct assay
15528197 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor LBX1

lady bird-like homeobox 1 homolog

ladybird homeobox protein homolog 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07546 LBX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lbx1 NCBI NCBI:10660