DDX53 - DEAD-box helicase 53 Gene

Also Known as CAGE; CT26

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 168400

About DDX53

Cytogenetic location: Xp22.11 Genomic coordinates (GRCh38): X:22,999,960-23,003,589 (from NCBI)

This gene has 1 transcript (splice variant), 10 orthologues and 38 paralogues.

Summary

This intronless gene encodes a protein which contains several domains found in members of the DEAD-box helicase protein family. Other members of this protein family participate in ATP-dependent RNA unwinding. [provided by RefSeq, Sep 2011]

DDX53 Products (1)

mRNA Protein Name
NM_182699.4 NP_874358.2 DEAD box protein 53

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DDX53 Protein Structure

KH_1

KH_1: KH domain (53 - 109)

DEAD

DEAD: DEAD/DEAH box helicase (246 - 416)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (488 - 562)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 631 a.a.
Protein Preferred Names Protein Names

DEAD box protein 53

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 53

Related Diseases

Diseases Alias
Medullary Colon Carcinoma
Congenital Myasthenic Syndrome 7

  • Cms7

  • Congenital Myasthenic Syndrome 7 Presynaptic

  • Myasthenic Syndrome, Congenital, Type 7, Presynaptic
Leukodystrophy, Hypomyelinating, 8, With Or Without Oligodontia And/Or Hypogonadotropic Hypogonadism

  • Hypomyelinating Leukodystrophy 8 With Or Without Oligodontia And-Or Hypogonadotropic Hypogonadism

  • HLD8

  • Cerebellar Hypoplasia With Endosteal Sclerosis

  • 4h Leukodystrophy 2

  • Endosteal Sclerosis-Cerebellar Hypoplasia Syndrome

  • Leukodystrophy, Hypomyelinating, Type 8, With/Without Oligodontia And/Or Hypogonadotropic Hypogonadism
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Breast Adenocarcinoma

  • Mammary Adenocarcinoma

  • Adenocarcinoma Of Breast
Colonic Benign Neoplasm

  • Colon Neoplasm

  • Colonic Mass

  • Colonic Tumor

  • Neoplasm Of Colon

  • Neoplasm Of The Colon

  • Colonic Neoplasms

  • Colon Cancer

  • Colon Carcinoma Nos

  • Colonic Cancer

  • Metastatic Colon Cancer Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03658 DDX53 Human Pre-designed siRNA Set A Pre-designed Set / Unkown