Llgl1 - LLGL1 scribble cell polarity complex component Gene

Also Known as Lgl1; Mgl1; Llglh

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16897

Summary

Predicted to enable GTPase activator activity; enzyme binding activity; and Myosin II binding activity. Acts upstream of or within maintenance of apical/basal cell polarity. Located in several cellular components, including basolateral plasma membrane; cytoskeleton; and myelin sheath abaxonal region. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human LLGL1 (LLGL scribble cell polarity complex component 1). [provided by Alliance of Genome Resources, Apr 2022]

Llgl1 Products (5)

mRNA Protein Name
NM_001159404.2 NP_001152876.1 lethal(2) giant larvae protein homolog 1 isoform 3
NM_001159405.2 NP_001152877.1 lethal(2) giant larvae protein homolog 1 isoform 1
NM_001378836.1 NP_001365765.1 lethal(2) giant larvae protein homolog 1 isoform 4
NM_001378837.1 NP_001365766.1 lethal(2) giant larvae protein homolog 1 isoform 5
NM_008502.3 NP_032528.1 lethal(2) giant larvae protein homolog 1 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within maintenance of apical/basal cell polarity IMP
IMP: Inferred from mutant phenotype
15037549 MGI
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
22333836 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
15037549 MGI
located in cytoskeleton IDA
IDA: Inferred from direct assay
7542763 MGI
located in myelin sheath abaxonal region IDA
IDA: Inferred from direct assay
20237282 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lethal(2) giant larvae protein homolog 1

  • LLGL

  • lethal giant larvae homolog 1

  • mgl-1

  • mlgl

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07700 LLGL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Llgl1 NCBI NCBI:3996