Lnx1 - ligand of numb-protein X 1 Gene

Also Known as Lnx

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16924

Summary

Enables PDZ domain binding activity; identical protein binding activity; and ubiquitin-protein transferase activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Located in cytoplasm. Is expressed in several structures, including brain; heart; lung; nasal epithelium; and spinal cord. Orthologous to human LNX1 (ligand of numb-protein X 1). [provided by Alliance of Genome Resources, Apr 2022]

Lnx1 Products (6)

mRNA Protein Name
NM_001159577.1 NP_001153049.1 E3 ubiquitin-protein ligase LNX isoform 1
NM_001159578.1 NP_001153050.1 E3 ubiquitin-protein ligase LNX isoform 3
NM_001159579.1 NP_001153051.1 E3 ubiquitin-protein ligase LNX isoform 2 precursor
NM_001159580.1 NP_001153052.1 E3 ubiquitin-protein ligase LNX isoform 5 precursor
NM_001359074.1 NP_001346003.1 E3 ubiquitin-protein ligase LNX isoform 3
NM_010727.4 NP_034857.3 E3 ubiquitin-protein ligase LNX isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables PDZ domain binding IDA
IDA: Inferred from direct assay
9535908 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
11922143 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9535908 MGI
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
11782429 MGI
Biological Process GO Annotation Evidence References Source
involved in synapse maturation IDA
IDA: Inferred from direct assay
30185604 MGI
involved in synapse maturation IMP
IMP: Inferred from mutant phenotype
30185604 MGI
acts upstream of or within ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
11782429 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11782429 MGI
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
30185604 MGI
is active in hippocampal mossy fiber to CA3 synapse IMP
IMP: Inferred from mutant phenotype
30185604 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
30185604 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
30185604 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
30185604 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase LNX

  • RING-type E3 ubiquitin transferase LNX

  • ligand of Numb protein X 1

  • ligand of Numb-binding protein 1

  • numb-binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07732 LNX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lnx1 NCBI NCBI:84708