Irag2 - inositol 1,4,5-triphosphate receptor associated 2 Gene

Also Known as Jaw1; Lrmp; D6Int3; D6Int4; D6Int5; D6Int7; D6Int8

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16970

Summary

Enables microtubule binding activity. Involved in nucleus organization. Located in endoplasmic reticulum membrane and nuclear envelope. Is integral component of endoplasmic reticulum membrane. Is expressed in brain; liver; and thymus primordium. Orthologous to human IRAG2 (inositol 1,4,5-triphosphate receptor associated 2). [provided by Alliance of Genome Resources, Apr 2022]

Irag2 Products (5)

mRNA Protein Name
NM_001281980.1 NP_001268909.1 inositol 1,4,5-triphosphate receptor associated 2 isoform 1
NM_001281981.1 NP_001268910.1 inositol 1,4,5-triphosphate receptor associated 2 isoform 2
NM_001361633.1 NP_001348562.1 inositol 1,4,5-triphosphate receptor associated 2 isoform 4
NM_001368864.1 NP_001355793.1 inositol 1,4,5-triphosphate receptor associated 2 isoform 2
NM_008511.4 NP_032537.3 inositol 1,4,5-triphosphate receptor associated 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
29878215 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20071408 MGI
Biological Process GO Annotation Evidence References Source
involved in nucleus organization IMP
IMP: Inferred from mutant phenotype
29878215 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
8798562 MGI
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
8021504 MGI
located in nuclear envelope IDA
IDA: Inferred from direct assay
29878215 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inositol 1,4,5-triphosphate receptor associated 2

  • lymphoid-restricted membrane protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06892 IRAG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Irag2 NCBI NCBI:4033