QSOX2 - quiescin sulfhydryl oxidase 2 Gene
Also Known as SOXN; QSCN6L1
Species: Homo sapiens
About QSOX2
This gene has 2 transcripts (splice variants), 199 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 8.6), spleen (RPKM 7.1) and 25 other tissues.
Summary
QSOX2 is a member of the sulfhydryl oxidase/quiescin-6 (Q6) family (QSOX1; MIM 603120) that regulates the sensitization of neuroblastoma cells for IFN-gamma (IFNG; MIM 147570)-induced cell death (Wittke et al., 2003 [PubMed 14633699]).[supplied by OMIM, Jun 2009]
QSOX2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_181701.4 | NP_859052.3 | sulfhydryl oxidase 2 precursor |
QSOX2 Protein Structure
Thioredoxin: Thioredoxin (74 - 150)
Evr1_Alr: Erv1 / Alr family (430 - 532)
- 0
- 200
- 400
- 600
- 698 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sulfhydryl oxidase 2 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Neuroblastoma |
|
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| Deafness, Autosomal Recessive 33 |
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| Deafness, Autosomal Dominant 50 |
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| Deafness, Autosomal Recessive 79 |
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| Pituitary Adenoma 5, Multiple Types |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | QSOX2 | RGD | RGD:1584720 |
| Felis catus | QSOX2 | VGNC | VGNC:64462 |
| Mus musculus | QSOX2 | MGD | MGI:2387194 |
| Macaca mulatta | QSOX2 | VGNC | VGNC:76568 |
| Canis familiaris | QSOX2 | VGNC | VGNC:45239 |
| Bos taurus | QSOX2 | VGNC | VGNC:33606 |
| Others | QSOX2 | NCBI |