2. Gene
  3. Lrrfip1 - leucine rich repeat (in FLII) interacting protein 1 Gene

Lrrfip1 - leucine rich repeat (in FLII) interacting protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Fliiap1

Gene ID: 16978 | Gene type: protein coding

About Lrrfip1

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Acts upstream of or within positive regulation of NF-kappaB transcription factor activity. Predicted to be located in cytosol and plasma membrane. Is expressed in several structures, including brain; gallbladder; genitourinary system; gut; and integumental system. Orthologous to human LRRFIP1 (LRR binding FLII interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Lrrfip1 Products(4)

mRNA Protein Name
NM_001111311.1 NP_001104781.1 leucine-rich repeat flightless-interacting protein 1 isoform 1
NM_001111312.1 NP_001104782.1 leucine-rich repeat flightless-interacting protein 1 isoform 3
NM_001310732.1 NP_001297661.1 leucine-rich repeat flightless-interacting protein 1 isoform 4
NM_008515.4 NP_032541.1 leucine-rich repeat flightless-interacting protein 1 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16990252 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of NF-kappaB transcription factor activity IDA
IDA: Inferred from direct assay
19265123 MGI
acts upstream of or within positive regulation of NF-kappaB transcription factor activity IGI
IGI: Inferred from genetic interaction
19265123 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat flightless-interacting protein 1

FLAP (FLI LRR associated protein)

FLI-LRR-associated protein 1

H186 FLAP

LRR FLII-interacting protein 1

flap-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07830 LRRFIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrfip1 NCBI NCBI:9208