Atp6v0c - ATPase H+ transporting V0 subunit C Gene

Also Known as Atp6c; Atp6l

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 170667

Summary

Predicted to enable ubiquitin protein Ligase binding activity. Involved in negative regulation of autophagic cell death and positive regulation of ERK1 and ERK2 cascade. Located in Golgi apparatus; lysosome; and synaptic vesicle. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Orthologous to human ATP6V0C (ATPase H+ transporting V0 subunit c). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v0c Products (1)

mRNA	Protein	Name
NM_130823.4	NP_570836.1	V-type proton ATPase 16 kDa proteolipid subunit c

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	References	Source
involved in negative regulation of autophagic cell death	IMP IMP: Inferred from mutant phenotype	17845832	RGD
involved in positive regulation of ERK1 and ERK2 cascade	IMP IMP: Inferred from mutant phenotype	17845832	RGD

Cellular Component GO Annotation	Evidence	References	Source
located in synaptic vesicle	IDA IDA: Inferred from direct assay	8567678	RGD
is active in synaptic vesicle membrane	EXP EXP: Inferred from Experiment	32165585	RGD
is active in synaptic vesicle membrane	IDA IDA: Inferred from direct assay	32165585	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase 16 kDa proteolipid subunit	ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit C ATPase, H+ transporting, lysosomal 1 ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c ATPase, H+ transporting, lysosomal V0 subunit C V-ATPase 16 kDa proteolipid subunit V-ATP

Protein Preferred Names

Protein Names

V-type proton ATPase 16 kDa proteolipid subunit c

V-type proton ATPase 16 kDa proteolipid subunit

ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit C
ATPase, H+ transporting, lysosomal 1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATPase, H+ transporting, lysosomal V0 subunit C
V-ATPase 16 kDa proteolipid subunit
V-ATP

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01220	ATP6V0C Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Atp6v0c	NCBI	NCBI:527