1. Gene
  2. Atp6v0c - ATPase H+ transporting V0 subunit C Gene

Atp6v0c - ATPase H+ transporting V0 subunit C Gene

Rattus norvegicus

Also known as Atp6c; Atp6l

Gene ID: 170667 | Gene type: protein coding

About Atp6v0c

Summary

Predicted to enable ubiquitin protein Ligase binding activity. Involved in negative regulation of autophagic cell death and positive regulation of ERK1 and ERK2 cascade. Located in Golgi apparatus; lysosome; and synaptic vesicle. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Orthologous to human ATP6V0C (ATPase H+ transporting V0 subunit c). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v0c Products(1)

mRNA Protein Name
NM_130823.4 NP_570836.1 V-type proton ATPase 16 kDa proteolipid subunit c
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of autophagic cell death IMP
IMP: Inferred from mutant phenotype
17845832 RGD
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
17845832 RGD
Cellular Component GO Annotation Evidence Reference Source
located in synaptic vesicle IDA
IDA: Inferred from direct assay
8567678 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
32165585 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
32165585 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

V-type proton ATPase 16 kDa proteolipid subunit c

V-type proton ATPase 16 kDa proteolipid subunit

ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit C

ATPase, H+ transporting, lysosomal 1

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

ATPase, H+ transporting, lysosomal V0 subunit C

V-ATPase 16 kDa proteolipid subunit

V-ATP

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp6v0c NCBI NCBI:527