Nphs2 - NPHS2 stomatin family member, podocin Gene

Also known as podocin

About Nphs2

Summary

Predicted to be involved in actin Cytoskeleton reorganization and metanephric glomerular visceral epithelial cell development. Predicted to be located in cell-cell junction and membrane raft. Predicted to be intrinsic component of the cytoplasmic side of the plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Predicted to colocalize with slit diaphragm. Used to study membranous glomerulonephritis and proteinuria. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in nephrotic syndrome type 2. Orthologous to human NPHS2 (NPHS2 stomatin family member, podocin). [provided by Alliance of Genome Resources, Apr 2022]