Slco1a4 - solute carrier organic anion transporter family, member 1a4 Gene

Also Known as Oatp2; Slc21a5; Slco1a2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170698

Summary

Enables bile acid transmembrane transporter activity and organic anion transmembrane transporter activity. Involved in several processes, including bile acid signaling pathway; organic anion transport; and response to 17alpha-ethynylestradiol. Located in basal plasma membrane. Biomarker of Dubin-Johnson syndrome; cholestasis; and fatty liver disease. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2). [provided by Alliance of Genome Resources, Apr 2022]

Slco1a4 Products (2)

mRNA Protein Name
NM_131906.1 NP_571981.1 solute carrier organic anion transporter family member 1A4
NM_131906.1 NP_571981.1 solute carrier organic anion transporter family member 1A4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables bile acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
9294213 RGD
enables organic anion transmembrane transporter activity IDA
IDA: Inferred from direct assay
9294213 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
27090119 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
27090119 RGD
involved in sodium-independent organic anion transport IDA
IDA: Inferred from direct assay
9294213 RGD
Cellular Component GO Annotation Evidence References Source
located in basal plasma membrane IDA
IDA: Inferred from direct assay
18619525 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier organic anion transporter family member 1A4

  • OATP-B1

  • brain digoxin carrier protein

  • brain-specific organic anion transporter

  • organic anion transporter 2

  • sodium-independent organic anion-transporting polypeptide 2

  • solute carrier family 21 (organic anion transporter), member 5

  • solute carrier fami

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13055 SLC1A4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13351 SLCO1A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21934 Slc1a4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28450 Slc1a4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown