ATP2C1 - Atp2c1 ATPase secretory pathway Ca2+ transporting 1 Gene

Also Known as Spca1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170699

Summary

Enables P-type calcium transporter activity. Involved in calcium ion transport and cellular calcium ion homeostasis. Located in Golgi apparatus; cytoplasmic vesicle; and plasma membrane. Human ortholog(s) of this gene implicated in Hailey-Hailey disease. Orthologous to human ATP2C1 (ATPase secretory pathway Ca2+ transporting 1). [provided by Alliance of Genome Resources, Apr 2022]

ATP2C1 Products (1)

mRNA Protein Name
NM_131907.2 NP_571982.2 calcium-transporting ATPase type 2C member 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables P-type calcium transporter activity IDA
IDA: Inferred from direct assay
15328051 RGD
Biological Process GO Annotation Evidence References Source
involved in calcium ion transport IDA
IDA: Inferred from direct assay
15328051 RGD
involved in calcium ion transport IMP
IMP: Inferred from mutant phenotype
12967911 RGD
involved in intracellular calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
14747290 RGD
Cellular Component GO Annotation Evidence References Source
located in secretory granule IDA
IDA: Inferred from direct assay
14747290 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium-transporting ATPase type 2C member 1

  • ATP-dependent Ca(2+) pump PMR1

  • ATPase 2C1

  • ATPase, Ca++ transporting, type 2C, member 1

  • ATPase, Ca++-sequestering

  • Ca(2+)/Mn(2+)-ATPase 2C1

  • calcium-transporting ATPase 2C1

  • secretory pathway Ca(2+)-ATPase 1

  • secretory pathway Ca(2+)-transporting ATPase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01198 ATP2C1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ATP2C1 NCBI NCBI:27032