2. Gene
  3. ATP2C1 - Atp2c1 ATPase secretory pathway Ca2+ transporting 1 Gene

ATP2C1 - Atp2c1 ATPase secretory pathway Ca2+ transporting 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Spca1

Gene ID: 170699 | Gene type: protein coding

About ATP2C1

Summary

Enables P-type calcium transporter activity. Involved in calcium ion transport and cellular calcium ion homeostasis. Located in Golgi apparatus; cytoplasmic vesicle; and plasma membrane. Human ortholog(s) of this gene implicated in Hailey-Hailey disease. Orthologous to human ATP2C1 (ATPase secretory pathway Ca2+ transporting 1). [provided by Alliance of Genome Resources, Apr 2022]

ATP2C1 Products(1)

mRNA Protein Name
NM_131907.2 NP_571982.2 calcium-transporting ATPase type 2C member 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables P-type calcium transporter activity IDA
IDA: Inferred from direct assay
15328051 RGD
Biological Process GO Annotation Evidence Reference Source
involved in calcium ion transport IDA
IDA: Inferred from direct assay
15328051 RGD
involved in calcium ion transport IMP
IMP: Inferred from mutant phenotype
12967911 RGD
involved in intracellular calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
14747290 RGD
Cellular Component GO Annotation Evidence Reference Source
located in secretory granule IDA
IDA: Inferred from direct assay
14747290 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium-transporting ATPase type 2C member 1

ATP-dependent Ca(2+) pump PMR1

ATPase 2C1

ATPase, Ca++ transporting, type 2C, member 1

ATPase, Ca++-sequestering

Ca(2+)/Mn(2+)-ATPase 2C1

calcium-transporting ATPase 2C1

secretory pathway Ca(2+)-ATPase 1

secretory pathway Ca(2+)-transporting ATPase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01198 ATP2C1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ATP2C1 NCBI NCBI:27032