Pilrb1 - paired immunoglobin-like type 2 receptor beta 1 Gene

Also Known as Fdact; Pilrb; FDFACT

Species: Mus musculus

Gene Type: protein coding
Gene ID: 170741

Summary

Enables MHC class I protein binding activity. Involved in negative regulation of osteoclast differentiation. Acts upstream of or within myeloid dendritic cell activation. Located in plasma membrane. Orthologous to human PILRA (paired immunoglobin like type 2 receptor alpha) and PILRB (paired immunoglobin like type 2 receptor beta). [provided by Alliance of Genome Resources, Apr 2022]

Pilrb1 Products (1)

mRNA Protein Name
NM_133209.2 NP_573472.2 paired immunoglobulin-like type 2 receptor beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables MHC class I protein binding IDA
IDA: Inferred from direct assay
18802077 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14970179 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within myeloid dendritic cell activation IDA
IDA: Inferred from direct assay
14970179 MGI
involved in negative regulation of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
18802077 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
14970179 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

paired immunoglobulin-like type 2 receptor beta

  • activating receptor PILR-beta

  • cell surface receptor FDFACT

  • immunoglobulin-like cell surface receptor FDFACT, activating counterpart

Recombinant Pilrb1 Proteins

Cat. No. Product Name Accession Purity
HY-P77143 PILR-beta Protein, Mouse (HEK293, Fc) Q2YFS2 (G29-G193) ≥ 90%, as determined by reducing SDS-PAGE.