Grin3b - glutamate ionotropic receptor NMDA type subunit 3B Gene

Also Known as NR3B; GluN3B; NMDAR3B

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170796

Summary

Enables several functions, including glycine binding activity; neurotransmitter binding activity; and neurotransmitter receptor activity. Involved in ionotropic glutamate receptor signaling pathway. Part of NMDA selective glutamate receptor complex. Is active in hippocampal mossy fiber to CA3 synapse. Is integral component of postsynaptic density membrane. Orthologous to human GRIN3B (glutamate ionotropic receptor NMDA type subunit 3B). [provided by Alliance of Genome Resources, Apr 2022]

Grin3b Products (1)

mRNA Protein Name
NM_133308.2 NP_579842.2 glutamate receptor ionotropic, NMDA 3B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glycine binding IDA
IDA: Inferred from direct assay
11823786 RGD
enables monoatomic cation channel activity IDA
IDA: Inferred from direct assay
11823786 RGD
enables neurotransmitter receptor activity IDA
IDA: Inferred from direct assay
11823786 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to glycine IDA
IDA: Inferred from direct assay
11823786 RGD
involved in ionotropic glutamate receptor signaling pathway IDA
IDA: Inferred from direct assay
11823786 RGD
Cellular Component GO Annotation Evidence References Source
part of NMDA selective glutamate receptor complex IDA
IDA: Inferred from direct assay
11823786 RGD
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
23159309 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
23159309 RGD
is active in presynaptic active zone membrane IDA
IDA: Inferred from direct assay
23159309 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutamate receptor ionotropic, NMDA 3B

  • N-methyl-D-aspartate receptor subtype 3B

  • glutamate [NMDA] receptor subunit 3B

  • glutamate receptor, ionotropic, N-methyl-D-aspartate 3B

  • glutamate receptor, ionotropic, NMDA3B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05807 GRIN3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grin3b NCBI NCBI:116444