Grin3b - glutamate ionotropic receptor NMDA type subunit 3B Gene

Rattus norvegicus

Also known as NR3B; GluN3B; NMDAR3B

Gene ID: 170796 | Gene type: protein coding

About Grin3b

Summary

Enables several functions, including glycine binding activity; neurotransmitter binding activity; and neurotransmitter receptor activity. Involved in ionotropic glutamate receptor signaling pathway. Part of NMDA selective glutamate receptor complex. Is active in hippocampal mossy fiber to CA3 synapse. Is integral component of postsynaptic density membrane. Orthologous to human GRIN3B (glutamate ionotropic receptor NMDA type subunit 3B). [provided by Alliance of Genome Resources, Apr 2022]

Grin3b Products(1)

mRNA	Protein	Name
NM_133308.2	NP_579842.2	glutamate receptor ionotropic, NMDA 3B precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables glycine binding	IDA IDA: Inferred from direct assay	11823786	RGD
enables monoatomic cation channel activity	IDA IDA: Inferred from direct assay	11823786	RGD
enables neurotransmitter receptor activity	IDA IDA: Inferred from direct assay	11823786	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to glycine	IDA IDA: Inferred from direct assay	11823786	RGD
involved in ionotropic glutamate receptor signaling pathway	IDA IDA: Inferred from direct assay	11823786	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of NMDA selective glutamate receptor complex	IDA IDA: Inferred from direct assay	11823786	RGD
is active in hippocampal mossy fiber to CA3 synapse	IDA IDA: Inferred from direct assay	23159309	RGD
is active in postsynaptic density membrane	IDA IDA: Inferred from direct assay	23159309	RGD
is active in presynaptic active zone membrane	IDA IDA: Inferred from direct assay	23159309	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

glutamate receptor ionotropic, NMDA 3B

N-methyl-D-aspartate receptor subtype 3B	glutamate [NMDA] receptor subunit 3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	glutamate receptor, ionotropic, NMDA3B

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05807	GRIN3B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Grin3b	NCBI	NCBI:116444

Name
Email *

	Sorry, but the email address you supplied was invalid.